Question detail
CGEQ24: Which experimental interpretation best tests Explain transcriptional stimulation and inhibition by transcription factors. using chromatin immunoprecipitation?
Try the question, check the answer, then read the explanation to understand the curriculum point.
At a glance
MCQ
Type
practice
Style
Topic
Control of gene expression official content
Question
- A. CGEQ24: Use chromatin immunoprecipitation. Independent variable: antibody identity. Dependent variable: enriched promoter reads. Controlled variable: sonication time. Method: identify the independent variable, dependent variable and controlled variable; keep controls constant; evaluate validity, reliability, accuracy, precision, uncertainty, risk, limitation, conclusion and improvement. Link the result to Explain transcriptional stimulation and inhibition by transcription factors.; transcription makes RNA and translation makes polypeptide.
- B. CGEQ24: Change antibody identity and sonication time together, then ignore uncertainty and controls.
- C. CGEQ24: Record enriched promoter reads without a method, dependent variable or evaluation.
- D. CGEQ24: Describe gene expression generally but omit the controlled variable and conclusion.
Answer
The correct answer is: CGEQ24: Use chromatin immunoprecipitation. Independent variable: antibody identity. Dependent variable: enriched promoter reads. Controlled variable: sonication time. Method: identify the independent variable, dependent variable and controlled variable; keep controls constant; evaluate validity, reliability, accuracy, precision, uncertainty, risk, limitation, conclusion and improvement. Link the result to Explain transcriptional stimulation and inhibition by transcription factors.; transcription makes RNA and translation makes polypeptide.
Explanation
For this question, start with the A-Level concept in Regulation of transcription and translation, then connect it to the scenario using transcription factor and a clear cause-and-effect chain. CGEQ24: The option is correct because it states method, independent variable, dependent variable, controlled variable, controls, evaluation and a valid conclusion for chromatin immunoprecipitation. Distractors usually fail because they reverse the mechanism, use the wrong scale of organisation, or describe a related topic without answering the exact objective.
Common mistake
Regulation of transcription and translation common mistake 1
Giving a vague answer instead of directly addressing: Explain transcriptional stimulation and inhibition by transcription factors..
Answer by clearly explaining how to explain transcriptional stimulation and inhibition by transcription factors..
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