Question detail

Explain how the structure of an amino acid allows it to act as a zwitterion.

Try the question, check the answer, then read the explanation to understand the curriculum point.

At a glance

Question

Type

exam_style

Style

Topic

Amino acids, proteins and DNA (A-level only)

Question

Explain how the structure of an amino acid allows it to act as a zwitterion.

Answer

An amino acid acts as a zwitterion because it has both a positively charged amine group and a negatively charged carboxylate group at physiological pH, resulting in a net charge of zero.

Explanation

This answer is strong as it clearly describes the dual charge characteristic of zwitterions, linking it to the structure of amino acids. The question tests understanding of amino acid behavior in different pH environments, which is crucial for biochemistry.

Common mistake

Confusing Functional Groups

Students often describe amino acids without clearly identifying the presence of both amine (-NH2) and carboxylic acid (-COOH) functional groups.

To fix this, remember that an amino acid contains both an amine group and a carboxylic acid group. For example, the general structure of an amino acid can be represented as R-CH(NH2)-COOH, where R represents the variable side chain. Clearly state both functional groups when describing amino acids.

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