Learning objective
Relate altered amino acid sequences to protein structure and function.
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Topic
Control of gene expression official content
Subtopic
Alteration of the sequence of bases in DNA can alter the structure of proteins
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Quick explanation
Relate altered amino acid sequences to protein structure and function
- This point belongs to Control of gene expression official content, especially Alteration of the sequence of bases in DNA can alter the structure of proteins.
- You need to be able to relate altered amino acid sequences to protein structure and function.
- The key ideas to know are protein structure and amino acid sequence.
- Use the linked flashcards and practice questions to check recall, then practise applying the idea in an exam-style answer.
Key concepts
Why it matters
This objective helps connect Alteration of the sequence of bases in DNA can alter the structure of proteins to exam-style questions, flashcards, and revision notes for Control of gene expression official content.
Quick student answer
Which of the following best describes how a mutation in the DNA sequence can affect protein function?
Direct answer
A mutation in the DNA sequence can lead to changes in the amino acid sequence of a protein, which may alter its tertiary structure and thus its function.
Key terms
- Mutation: A change in the nucleotide sequence of DNA that can lead to alterations in protein structure and function.
- Amino Acid Sequence: The order of amino acids in a protein, which determines its structure and function.
Common trap
Confusing mutations with all changes in DNA: Clarify that mutations specifically refer to changes that can affect protein coding sequences and potentially alter protein function.
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Revision notestopic notes
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Open revision notesRelated learning objectives
- Explain how base-sequence changes can alter amino acid sequences.
Alteration of the sequence of bases in DNA can alter the structure of proteins
- Explain how mutations can affect phenotype.
Alteration of the sequence of bases in DNA can alter the structure of proteins
- Interpret mutation information in unfamiliar contexts.
Alteration of the sequence of bases in DNA can alter the structure of proteins
- Explain that cell specialisation results from translation of only part of the DNA.
Most of a cell's DNA is not translated
- Distinguish totipotent, pluripotent, multipotent and unipotent cells.
Most of a cell's DNA is not translated