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Learning objective

Explain condensation reactions forming the sugar-phosphate backbone.

Read the explanation, check the common trap, then practise with flashcards and questions.

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Topic

Amino acids, proteins and DNA (A-level only)

Subtopic

DNA chemistry (A-level only)

Aqa A Level ChemistryOrganic chemistry

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Quick explanation

Explain condensation reactions forming the sugar-phosphate backbone

  • This point belongs to Amino acids, proteins and DNA (A-level only), especially DNA chemistry (A-level only).
  • You need to be able to explain condensation reactions forming the sugar-phosphate backbone.
  • The key ideas to know are sugar and phosphate.
  • Use the linked flashcards and practice questions to check recall, then practise applying the idea in an exam-style answer.

Key concepts

sugarphosphate

Why it matters

This objective helps connect DNA chemistry (A-level only) to exam-style questions, flashcards, and revision notes for Amino acids, proteins and DNA (A-level only).

Quick student answer

Which of the following correctly describes the condensation reaction that forms the sugar-phosphate backbone of DNA?

Direct answer

B. Two nucleotides join together by forming a phosphodiester bond.

Key terms

  • Condensation Reaction: A chemical reaction in which two molecules combine to form a larger molecule, with the loss of a small molecule, typically water.
  • Phosphodiester Bond: A covalent bond that connects the phosphate group of one nucleotide to the sugar of another nucleotide in the DNA backbone.

Common trap

Confusing condensation with hydrolysis: Remember that condensation reactions build larger molecules by removing water, while hydrolysis reactions break down molecules by adding water.

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