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Cambridge IGCSE Biology revision notes

Diffusion Revision Notes

Cambridge IGCSE revision notes for Diffusion.

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Diffusion

CambridgeIGCSEBiologyMovement into and out of cells

Complete revision guide 1 of 5

Understanding Diffusion as Particle Movement

Diffusion is the net movement of particles from areas of higher concentration to lower concentration caused by their random motion, without requiring energy.

Syllabus source

Section 3, Topic 3.1, page 15, objective 1

Open source document ↗

What you should be able to do

  • ✓Describe how particles move randomly.
  • ✓Explain why particles move from high to low concentration.
  • ✓Understand diffusion as a passive process.
1

Random Motion of Particles

Particles such as molecules and ions are constantly moving in all directions unpredictably due to their kinetic energy.

This random motion means particles collide and spread out over time.

  • Particles move in random directions
  • Movement is continuous and constant
2

Concentration Gradient and Net Movement

When there is a difference in particle concentration between two areas, particles tend to spread from the area with more particles (higher concentration) to the area with fewer particles (lower concentration).

This results in a net movement of particles down the concentration gradient.

  • Particles move from high to low concentration
  • Movement continues until concentrations equalize
3

Diffusion as a Passive Process

Diffusion does not require energy input from cells or organisms; it happens naturally due to particle motion.

It is essential for processes like gas exchange and nutrient absorption in living organisms.

  • No energy required
  • Important for biological functions

At-a-glance summary

Comparison table

AspectDescription
Particle MotionRandom movement due to kinetic energy
Direction of Net MovementFrom higher to lower concentration
Energy RequirementNo external energy needed (passive)
ResultEqual distribution of particles over time

Active recall

Quick check

1. What causes particles to move during diffusion?

Their random motion due to kinetic energy.

2. In which direction do particles move overall in diffusion?

From areas of higher concentration to areas of lower concentration.

3. Does diffusion require energy from the cell?

No, diffusion is a passive process and does not require energy.

Complete revision guide 2 of 5

Energy Source Driving Diffusion

The energy that causes molecules and ions to move during diffusion comes from their own kinetic energy, which results in random motion without external energy input.

Syllabus source

Section 3, Topic 3.1, page 15, objective 2

Open source document ↗

What you should be able to do

  • ✓Identify kinetic energy as the source of diffusion energy.
  • ✓Explain why diffusion does not need external energy.
  • ✓Describe how random motion leads to diffusion.
1

Kinetic Energy of Particles

Molecules and ions possess kinetic energy, which is the energy of motion.

This energy causes them to move randomly in all directions constantly.

  • Kinetic energy = energy of motion
  • Particles move unpredictably due to kinetic energy
2

Random Motion Enables Diffusion

Because particles move randomly, they spread out from crowded areas to less crowded areas.

This spreading out is the basis of diffusion, moving substances down their concentration gradient.

  • Random motion causes particles to spread
  • Leads to net movement from high to low concentration
3

No External Energy Needed

Diffusion is a passive process powered by the particles' own kinetic energy.

Cells do not need to use energy to make diffusion happen.

  • Diffusion requires no external energy
  • Energy comes from particle motion itself

At-a-glance summary

Comparison table

FeatureExplanation
Energy SourceKinetic energy of molecules and ions
Particle MotionRandom movement caused by kinetic energy
Energy RequirementNo external or cellular energy needed
EffectParticles spread from high to low concentration

Active recall

Quick check

1. What type of energy causes particles to move during diffusion?

Kinetic energy.

2. Does diffusion require energy input from cells?

No, it is powered by the particles' own kinetic energy.

3. How does random motion relate to diffusion?

Random motion causes particles to spread from high to low concentration, resulting in diffusion.

Complete revision guide 3 of 5

Substances Moving Through Cell Membranes by Diffusion

Certain small substances like oxygen and carbon dioxide move into and out of cells by diffusion across the selectively permeable cell membrane without energy use.

Syllabus source

Section 3, Topic 3.1, page 15, objective 3

Open source document ↗

What you should be able to do

  • ✓Identify substances that enter and exit cells by diffusion.
  • ✓Understand diffusion across the cell membrane.
  • ✓Recognize that diffusion is passive and does not require energy.
1

Cell Membrane and Selective Permeability

The cell membrane controls what substances can enter or leave the cell.

It allows small molecules like oxygen and carbon dioxide to pass through by diffusion.

Larger molecules usually cannot diffuse directly through the membrane.

  • Cell membrane is selectively permeable
  • Allows small molecules to diffuse
  • Blocks large molecules
2

Diffusion of Oxygen and Carbon Dioxide

Oxygen moves from outside the cell, where its concentration is higher, into the cell by diffusion.

Carbon dioxide moves from inside the cell, where its concentration is higher, out into the surroundings by diffusion.

This exchange supports cellular respiration and waste removal.

  • Oxygen enters cells by diffusion
  • Carbon dioxide leaves cells by diffusion
3

Energy and Diffusion Across Membranes

Diffusion across the cell membrane is a passive process and does not require energy from the cell.

Movement occurs down concentration gradients until equilibrium is reached.

  • No energy required
  • Movement down concentration gradient

At-a-glance summary

Comparison table

SubstanceDirection of MovementReason
OxygenInto the cellHigher concentration outside, needed for respiration
Carbon dioxideOut of the cellHigher concentration inside, waste product to remove
Large moleculesGenerally cannot diffuseToo big to pass through membrane pores
Water (osmosis)Moves by osmosis, not diffusionMovement of water specifically through membrane

Active recall

Quick check

1. Name one substance that enters cells by diffusion.

Oxygen (O2).

2. Name one substance that leaves cells by diffusion.

Carbon dioxide (CO2).

3. Does diffusion across the cell membrane require energy?

No, it is a passive process.

Complete revision guide 4 of 5

Importance of Diffusion of Gases and Solutes in Living Organisms

Diffusion is essential for moving gases like oxygen and carbon dioxide, and solutes such as nutrients and wastes, across cell membranes to support respiration, metabolism, and waste removal without energy use.

Syllabus source

Section 3, Topic 3.1, page 15, objective 4

Open source document ↗

What you should be able to do

  • ✓Describe how diffusion supports oxygen uptake and carbon dioxide removal.
  • ✓Explain diffusion's role in nutrient and waste exchange.
  • ✓Understand diffusion as a passive process vital for organism function.
1

Gas Exchange by Diffusion

Oxygen diffuses from areas of higher concentration outside cells into cells where it is used for respiration.

Carbon dioxide, a waste product of respiration, diffuses out of cells where its concentration is higher into the surrounding fluid where it is lower.

This exchange is critical for cellular energy production and waste removal.

  • Oxygen enters cells by diffusion
  • Carbon dioxide leaves cells by diffusion
2

Movement of Nutrients and Waste Solutes

Nutrients dissolved in body fluids diffuse into cells to provide materials for growth and metabolism.

Waste substances produced by cells diffuse out into body fluids to be eliminated.

Diffusion maintains the balance of substances needed for cell survival.

  • Nutrients enter cells by diffusion
  • Waste products leave cells by diffusion
3

Diffusion Supports Life Processes Without Energy

Diffusion is a passive process that does not require energy from cells.

It helps maintain stable internal conditions by regulating the movement of gases and solutes.

In large organisms, diffusion is supplemented by circulatory systems to transport substances efficiently.

  • No energy required
  • Maintains homeostasis
  • Supports respiration and metabolism

At-a-glance summary

Comparison table

FunctionRole of Diffusion
Oxygen UptakeDiffuses into cells to support respiration
Carbon Dioxide RemovalDiffuses out of cells as waste
Nutrient SupplyDiffuses into cells for metabolism
Waste RemovalDiffuses out of cells to be eliminated
HomeostasisMaintains stable internal environment

Active recall

Quick check

1. How does oxygen reach cells?

By diffusion from higher concentration outside to lower concentration inside.

2. Why is diffusion important for removing carbon dioxide?

It allows carbon dioxide to move out of cells to prevent toxic buildup.

3. Does diffusion require energy from the cell?

No, diffusion is a passive process and does not require energy.

Complete revision guide 5 of 5

Factors Influencing the Rate of Diffusion

Diffusion rate depends on surface area, temperature, concentration gradient, and distance, all affecting how quickly particles move from high to low concentration.

Syllabus source

Section 3, Topic 3.1, page 15, objective 5

Open source document ↗

What you should be able to do

  • ✓Investigate how each factor affects diffusion rate.
  • ✓Explain the biological significance of these factors.
  • ✓Apply understanding to practical examples and experiments.
1

Surface Area

A larger surface area allows more particles to diffuse simultaneously, increasing the overall rate of diffusion. Biological structures like alveoli have large surface areas to maximize diffusion efficiency.

  • More surface area means more space for particles to cross.
  • Increasing surface area speeds up diffusion.
2

Temperature

Higher temperatures increase the kinetic energy of particles, causing them to move faster and collide more often, which speeds up diffusion.

  • Temperature rise increases particle movement speed.
  • Diffusion rate increases with temperature until other factors limit it.
3

Concentration Gradient

A steeper concentration gradient means a larger difference in concentration between two areas, providing a stronger driving force for particles to move from high to low concentration.

  • Greater concentration difference increases diffusion rate.
  • As gradient decreases, diffusion slows down.
4

Distance

The shorter the distance particles must travel, the faster diffusion occurs because particles have less space to cover.

  • Thin membranes reduce diffusion distance.
  • Shorter distance increases diffusion speed.

At-a-glance summary

Comparison table

FactorEffect on Diffusion RateBiological Example
Surface AreaIncreased surface area increases diffusion rateAlveoli in lungs have large surface area for gas exchange
TemperatureHigher temperature increases diffusion rateWarm blooded animals maintain body temperature for efficient diffusion
Concentration GradientSteeper gradient increases diffusion rateOxygen moves from alveoli (high) to blood (low)
DistanceShorter distance increases diffusion rateCapillary walls are thin to minimize diffusion distance

Active recall

Quick check

1. How does increasing surface area affect diffusion?

It increases the rate by allowing more particles to diffuse at once.

2. Why does temperature affect diffusion rate?

Higher temperature increases particle movement speed, speeding diffusion.

3. What is the effect of a steeper concentration gradient?

It increases the diffusion rate by providing a stronger driving force.

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