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Cambridge IGCSE Biology revision notes

Hormones Revision Notes

Cambridge IGCSE revision notes for Hormones.

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Hormones

CambridgeIGCSEBiologyCoordination and response

Complete revision guide 1 of 6

Hormones: Chemical Messengers in the Body

Hormones are chemicals produced by glands that travel in the blood to specific target organs, where they change how these organs function to regulate body processes.

Syllabus source

Section 3, Topic 14.3, page 32, objective 1

Open source document ↗

What you should be able to do

  • ✓Define what a hormone is.
  • ✓Describe how hormones travel in the body.
  • ✓Explain how hormones affect target organs.
1

Definition and Production

Hormones are chemical substances produced by specialized glands in the body.

These glands release hormones directly into the bloodstream.

Each hormone is designed to affect specific organs or tissues called target organs.

  • Produced by glands.
  • Released into the blood.
  • Target specific organs.
2

Transport in the Blood

Once secreted, hormones travel through the bloodstream to reach their target organs.

The blood acts as a transport system distributing hormones throughout the body.

Only organs with specific receptors respond to a particular hormone.

  • Travel via bloodstream.
  • Reach target organs with matching receptors.
  • Do not affect all organs, only specific targets.
3

Effect on Target Organs

Hormones modify or regulate the function of their target organs.

This regulation helps maintain internal balance and coordinate body activities such as growth, metabolism, and reproduction.

The effect depends on the hormone and the organ it targets.

  • Change how target organs function.
  • Help regulate body processes.
  • Ensure coordinated responses.

At-a-glance summary

Comparison table

AspectHormones
Produced byGlands
Transported byBloodstream
TargetSpecific organs with receptors
FunctionModify or regulate organ activity

Active recall

Quick check

1. What is a hormone?

A chemical substance produced by a gland that travels in the blood and modifies the function of specific target organs.

2. How do hormones reach their target organs?

Hormones are transported by the blood through the bloodstream.

3. What do hormones do at their target organs?

They modify or regulate the function of the target organs.

Complete revision guide 2 of 6

Key Endocrine Glands and Their Hormones

Four important endocrine glands produce specific hormones: adrenal glands produce adrenaline, pancreas produces insulin, testes produce testosterone, and ovaries produce oestrogen.

Syllabus source

Section 3, Topic 14.3, page 32, objective 2

Open source document ↗

What you should be able to do

  • ✓Identify the adrenal glands and their hormone.
  • ✓Identify the pancreas and its hormone.
  • ✓Identify the testes and their hormone.
  • ✓Identify the ovaries and their hormone.
1

Adrenal Glands and Adrenaline

The adrenal glands are located above the kidneys and produce adrenaline.

Adrenaline prepares the body for rapid action during stress, triggering the 'fight or flight' response.

  • Located above kidneys.
  • Produce adrenaline.
  • Involved in stress response.
2

Pancreas and Insulin

The pancreas produces insulin, a hormone that regulates blood glucose levels.

Insulin helps lower blood sugar by enabling cells to absorb glucose.

  • Located near the stomach.
  • Produce insulin.
  • Regulate blood sugar levels.
3

Testes and Testosterone

The testes are male reproductive glands that produce testosterone.

Testosterone controls male secondary sexual characteristics such as facial hair and muscle growth.

  • Male reproductive glands.
  • Produce testosterone.
  • Control male sexual development.
4

Ovaries and Oestrogen

The ovaries are female reproductive glands that produce oestrogen.

Oestrogen regulates female reproductive development and the menstrual cycle.

  • Female reproductive glands.
  • Produce oestrogen.
  • Control female sexual development and menstrual cycle.

At-a-glance summary

Comparison table

GlandHormone ProducedPrimary Function
Adrenal glandsAdrenalinePrepares body for 'fight or flight'
PancreasInsulinLowers blood glucose levels
TestesTestosteroneControls male sexual characteristics
OvariesOestrogenRegulates female reproductive system

Active recall

Quick check

1. Which hormone is produced by the adrenal glands?

Adrenaline is produced by the adrenal glands.

2. What hormone does the pancreas produce?

The pancreas produces insulin.

3. Which gland produces testosterone?

The testes produce testosterone.

4. Which hormone is produced by the ovaries?

Oestrogen is produced by the ovaries.

Complete revision guide 3 of 6

Adrenaline and the 'Fight or Flight' Response

Adrenaline is released during stress and causes increased breathing rate, heart rate, and pupil size to prepare the body for rapid action.

Syllabus source

Section 3, Topic 14.3, page 32, objective 3

Open source document ↗

What you should be able to do

  • ✓Describe when adrenaline is released.
  • ✓Explain the effects of adrenaline on breathing rate.
  • ✓Explain the effects of adrenaline on heart rate.
  • ✓Explain the effects of adrenaline on pupil size.
1

Release of Adrenaline

Adrenaline is a hormone secreted by the adrenal glands during stressful or dangerous situations.

Its release triggers the body's 'fight or flight' response, preparing it for rapid action.

  • Released by adrenal glands.
  • Triggered by stress or danger.
  • Prepares body for quick response.
2

Effects on Breathing Rate

Adrenaline increases the breathing rate to supply more oxygen to the muscles.

This helps meet the increased oxygen demand during stress or physical activity.

  • Breathing rate increases.
  • More oxygen enters the lungs.
  • Supports muscle activity.
3

Effects on Heart Rate

Adrenaline causes the heart to beat faster, increasing heart rate.

This pumps oxygenated blood more quickly to muscles and vital organs.

  • Heart rate increases.
  • Faster blood circulation.
  • Improves oxygen delivery.
4

Effects on Pupil Size

Adrenaline causes the pupils to dilate (increase in size).

Larger pupils allow more light into the eyes, improving vision in stressful situations.

  • Pupils dilate.
  • More light enters the eyes.
  • Enhances vision.

At-a-glance summary

Comparison table

Effect of AdrenalinePurpose
Increased breathing rateSupplies more oxygen to muscles
Increased heart rateCirculates oxygenated blood faster
Increased pupil sizeAllows more light for better vision
OverallPrepares body for rapid action during stress

Active recall

Quick check

1. What hormone is released during the 'fight or flight' response?

Adrenaline is released during the 'fight or flight' response.

2. Name one effect of adrenaline on the respiratory system.

Adrenaline increases the breathing rate.

3. How does adrenaline affect the heart?

It increases the heart rate.

4. What happens to the pupils when adrenaline is released?

The pupils dilate (increase in size).

Complete revision guide 4 of 6

Comparing Nervous and Hormonal Control Mechanisms

Nervous and hormonal systems regulate body functions differently in terms of response speed and effect duration.

Syllabus source

Section 3, Topic 14.3, page 32, objective 4

Open source document ↗

What you should be able to do

  • ✓Understand how nervous and hormonal systems transmit signals.
  • ✓Compare the speed of response between nervous and hormonal control.
  • ✓Compare the duration of effects between nervous and hormonal control.
1

Signal Transmission Methods

The nervous system transmits signals as electrical impulses along neurons, allowing rapid communication to specific target cells.

The hormonal system releases chemical messengers called hormones into the bloodstream, which travel to target organs more slowly and affect multiple tissues.

  • Nervous system uses electrical impulses via neurons.
  • Hormonal system uses chemical signals (hormones) transported by blood.
2

Speed of Response

Nervous responses are very fast because electrical impulses travel quickly along nerve cells, enabling immediate reactions such as reflexes.

Hormonal responses are slower since hormones must circulate through the blood to reach target cells, causing a delay before effects begin.

  • Nervous system responses are rapid.
  • Hormonal system responses are slower due to blood transport.
3

Duration of Effects

Nervous system effects are usually short-lived; once the electrical impulse stops, the response ends quickly.

Hormonal effects last longer because hormones remain in the bloodstream and continue to influence target organs after release.

  • Nervous responses are brief.
  • Hormonal responses are prolonged.

At-a-glance summary

Comparison table

FeatureNervous ControlHormonal Control
Signal TypeElectrical impulsesChemical hormones
Transport MediumNeurons (nerve cells)Bloodstream
Speed of ResponseVery fastSlower
Duration of EffectShort-livedLong-lasting
Target SpecificitySpecific cells or tissuesMultiple organs or tissues

Active recall

Quick check

1. What type of signals does the nervous system use?

Electrical impulses transmitted by neurons.

2. Why are nervous responses faster than hormonal responses?

Because electrical impulses travel quickly along neurons, while hormones travel slowly in the blood.

3. Which system produces longer-lasting effects, nervous or hormonal?

Hormonal system produces longer-lasting effects because hormones remain in the bloodstream.

Complete revision guide 5 of 6

Glucagon: Hormone Secreted by the Pancreas

Glucagon is a hormone produced by the pancreas that raises blood glucose levels by stimulating glycogen breakdown in the liver.

Syllabus source

Section 3, Topic 14.3, page 32, objective 5

Open source document ↗

What you should be able to do

  • ✓Identify glucagon as a pancreatic hormone.
  • ✓Understand glucagon's role in increasing blood glucose.
  • ✓Know how glucagon acts on the liver to release glucose.
1

Source of Glucagon

Glucagon is secreted by specialized cells in the pancreas when blood glucose levels fall too low.

It acts as a chemical messenger to regulate blood sugar balance.

  • Produced by pancreas.
  • Released when blood glucose is low.
2

Function of Glucagon

Glucagon signals the liver to convert stored glycogen into glucose.

This glucose is then released into the bloodstream to raise blood sugar levels.

This process ensures a steady supply of glucose for energy, especially during fasting or between meals.

  • Stimulates glycogen breakdown in liver.
  • Raises blood glucose concentration.
  • Works opposite to insulin to maintain balance.
3

Importance in Blood Sugar Regulation

Glucagon helps prevent hypoglycemia (low blood sugar) by increasing glucose availability.

It complements insulin, which lowers blood glucose, together maintaining homeostasis.

  • Prevents low blood sugar.
  • Balances insulin effects.

At-a-glance summary

Comparison table

AspectGlucagon
SourcePancreas
Trigger for ReleaseLow blood glucose levels
Target OrganLiver
ActionStimulates glycogen breakdown to glucose
Effect on Blood GlucoseRaises concentration

Active recall

Quick check

1. Which organ secretes glucagon?

The pancreas.

2. What effect does glucagon have on blood glucose?

It raises blood glucose concentration.

3. How does glucagon increase blood glucose?

By stimulating the liver to break down glycogen into glucose.

Complete revision guide 6 of 6

Adrenaline's Role in Metabolic Regulation

Adrenaline increases blood glucose levels and heart rate to prepare the body for rapid activity during stress.

Syllabus source

Section 3, Topic 14.3, page 32, objective 6

Open source document ↗

What you should be able to do

  • ✓Describe how adrenaline raises blood glucose.
  • ✓Explain how adrenaline increases heart rate.
  • ✓Understand how these effects prepare the body for 'fight or flight'.
1

Effect on Blood Glucose

Adrenaline stimulates the liver to break down glycogen into glucose, increasing blood glucose levels.

This provides extra energy for muscles during stressful or emergency situations.

  • Raises blood glucose by glycogen breakdown in liver.
  • Supplies energy for rapid muscle activity.
2

Effect on Heart Rate

Adrenaline increases heart rate, which boosts blood circulation.

Improved circulation delivers more oxygen and nutrients to tissues, supporting increased metabolic demands.

  • Increases heart rate.
  • Enhances blood flow and oxygen delivery.
3

Overall Metabolic Impact

By raising blood glucose and heart rate, adrenaline prepares the body for quick, intense physical activity.

These changes support the 'fight or flight' response to stress or danger.

  • Prepares body for rapid action.
  • Increases metabolic activity.

At-a-glance summary

Comparison table

EffectAdrenaline
Blood GlucoseIncreases by stimulating glycogen breakdown
Heart RateIncreases to improve circulation
PurposePrepare body for rapid physical activity
TriggerStress or danger

Active recall

Quick check

1. How does adrenaline affect blood glucose levels?

It raises blood glucose by stimulating glycogen breakdown in the liver.

2. What effect does adrenaline have on heart rate?

It increases heart rate to improve blood circulation.

3. Why does adrenaline increase blood glucose and heart rate?

To prepare the body for rapid physical activity during stress or danger.

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